Role of radiotherapy in the management of brain metastases of NSCLC – Decision criteria in clinical routine

Abstract Background Whole brain radiotherapy (WBRT) is a common treatment option for metastases secondary to non-small cell lung cancer (NSCLC). Data from the QUARTZ trial suggest that WBRT can be omitted in selected patients and treated with optimal supportive care alone. Nevertheless, still widely used treat NSCLC. We analysed decision criteria influencing selection among European radiation oncology experts. Methods Twenty-two experts as by Society Therapeutic Radiation Oncology (ESTRO) previous projects Advisory Committee on Practice (ACROP) were asked describe their strategies management of Treatment subsequently converted into trees agreement discrepancies. Results Eight (suitability SRS, performance status, symptoms, eligibility targeted therapy, extra-cranial tumour control, age, prognostic scores “Zugzwang” (the compulsion treat)) identified. was recommended majority symptomatic not suitable radiosurgery or fractionated stereotactic radiotherapy. There also tendency use ALK/EGFR/ROS1 negative NSCLC setting. Conclusion Despite results